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Osteoimmunology: Interactions of the Immune and Skeletal...

Osteoimmunology: Interactions of the Immune and Skeletal Systems

Joseph Lorenzo, Mark Horowitz, Yongwon Choi, Hiroshi Takayanagi, Georg Schett (eds.)
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Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology.

This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics.

Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget’s disease, the genetics of bone disease, and bone cancer metastasis.

  • Explains the intricate interaction between the immune system and bone
  • Features detailed discussions of the key cellular and molecular mechanisms governing the homeostasis of the individual systems
  • Facilitates greater understanding of osteoimmunologic networks, their environments, and how this understanding leads to better treatments for human diseases involving both systems
年:
2015
出版:
2
出版社:
Academic Press
语言:
english
页:
376
ISBN 10:
0128005718
ISBN 13:
9780128005712
文件:
PDF, 16.68 MB
IPFS:
CID , CID Blake2b
english, 2015
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