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Missing Data in Clinical Studies (Statistics in Practice)

Missing Data in Clinical Studies (Statistics in Practice)

Geert Molenberghs, Michael Kenward
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Missing Data in Clinical Studies provides a comprehensive account of the problems arising when data from clinical and related studies are incomplete, and presents the reader with approaches to effectively address them. The text provides a critique of conventional and simple methods before moving on to discuss more advanced approaches. The authors focus on practical and modeling concepts, providing an extensive set of case studies to illustrate the problems described. Provides a practical guide to the analysis of clinical trials and related studies with missing data.Examines the problems caused by missing data, enabling a complete understanding of how to overcome them.Presents conventional, simple methods to tackle these problems, before addressing more advanced approaches, including sensitivity analysis, and the MAR missingness mechanism.Illustrated throughout with real-life case studies and worked examples from clinical trials.Details the use and implementation of the necessary statistical software, primarily SAS.Missing Data in Clinical Studies has been developed through a series of courses and lectures. Its practical approach will appeal to applied statisticians and biomedical researchers, in particular those in the biopharmaceutical industry, medical and public health organisations. Graduate students of biostatistics will also find much of benefit.
年:
2007
出版:
1
出版社:
Wiley
语言:
english
页:
526
ISBN 10:
0470849819
ISBN 13:
9780470849811
文件:
PDF, 16.23 MB
IPFS:
CID , CID Blake2b
english, 2007
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